A brief character rundown since I obviously love this show.
House: Serious antisocial genius with a disability. He had an infarction in his right leg and nearly lost it. He was in terrible pain and put into an induced coma. His then-girlfield, Stacy, had Dr. Lisa Cuddy perform an operation that would allow him to keep his leg, but with consequences. He now lives in chronic pain for which he takes a ****load of Vicodin and must walk with a cane. Stacy left him becasue he blames her for his condition. House has been described by reviewers as a modern, but medical Sherlock Holmes.
Dr. Lisa Cudd: House's boss as the hospital administrator. She tolerates his behavior because he can solve tough diagnoses that no one else can. Also, she's know House since college and is in ways guilty about his condition.
Dr. James Wilson: Perhaps House's only real friend. Although he also tolerates much of House's antics, he does call him on his bull****. He is the Watson to House's Holmes complex. Personally, he is a screw-up and has been left by his third wife.
Dr. Eric Foreman: House hired him for his street-smarts, but Foreman is a gifted neurologist. House often taunts him with issues of race and his criminal background. They fight constantly, but House respects him despite his refusal to show it.
Dr. Allison Cameron: One screwed up chick. She's attracted to the damaged, which is why she married a man with a terminal illness and is attracted to House. Her past is often the most sketchy of all the characters. While she is smart, she rarely shows a spine as she won't fight for her diagnosis and can't confront patients with difficult issues.
Dr. Robert Chase: A doctor who doesn't want to be a doctor. He's the son of a famous Australian doctor and he hates daddy so. He blames his father for the death of his mother, and perhaps for leaving the seminary to become a doctor just like daddy. He could be a great doctor, but he tends to show House some hero-worship and is developing some of the same bad habits when dealing with his work and patients.
Good show. The medical issues are a bit formulaic, but it's the subplots of the episodes between the lead characters that provide the overall arc of the show. Can't wait to see what they do next year.